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- Promotes weight loss - Suppresses appetite - Reduces blood lipids - Increases fat oxidation/mobilization - natural health medicine Promotes glycogen synthesis - Increases energy levels HCA can inhibit an enzyme in cells, citrate lyase, which is needed for the conversion of carbohydrates into fat. In the cell, carbohydrates are broken down into citrate compounds, which are then converted (by citrate lyase) into another compound; acetyl coenzyme natural health medicine A (acetyl CoA) – the metabolic building block for fat synthesis. By blocking the conversion of citrate into acetyl-CoA, HCA can suppress fat synthesis. Acetyl CoA is further converted into malonyl CoA, a compound which may block the actions of carnitine acyltransferase in shuttling fatty acids into the mitochondria to natural health medicine be burned. It is important to note, however, that the citrate lyase enzyme, is only active under conditions of carbohydrate overconsumption. In others words, unless you’re eating a lot of carbohydrate-type foods (bagels, pasta, potatoes) , and overloading your carbohydrate storage capacity (muscle and liver glycogen stores) there is natural health medicine no significant conversion of carbohydrates into fatty acids anyway (and HCA may not work for you) . If, however, you’re chowing down on low-fat highcarb foods at every meal, then your glycogen stores will be over-flowing and your citrate lyase enzymes are going to be working over time converting those natural health medicine excess carbs to fat. OK, so now that you’ve blocked the fat production, you have to do something with those excess carbs. They can’t be stored as glycogen because those stores in liver and muscle are already full, so it is thought that the body disposes of them by increasing natural health medicine carbohydrate oxidation (burning them) . As a result of these fully loaded glycogen stores, some researchers have suggested that a side effect of HCA supplementation may be a suppression of appetite – which would reduce food intake and promote weight loss .
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